The ocs system is an extracorporeal heart perfusion and monitoring system used for the resuscitation, preservation, and assessment of a donor’s hearts in a near-physiologic, normothermic, beating state intended for a potential transplant recipient. The system allows continuous monitoring of aortic pressure, lactate level, and coronary blood flow (Fig. 1). The system reduces cold storage time and increases the number of viable donors.
OC systems allow for longer preservation times and improved assessment of the organ’s condition, and thus may increase the number of patients that can receive a heart transplant. They also reduce the surgeon’s risk of iatrogenic complications and enable more peaceful mediastinal dissections . A study reported that OCS reduced decision-to-delivery times by 33%, and it significantly improves compliance with the 30-minute rule for organ transport to the recipient hospital.
OCS systems are designed to be a cost-effective alternative to standard organ transportation techniques. The technology can extend the preservation period by up to 24 hours, which may be helpful in countries where the availability of a donor is limited and in cases of vascular disease in the recipient. It is also useful for pretransplant evaluation of the recipient’s graft function, which can be done more comfortably and efficiently using OCS.
In a typical OCS procedure, the donor heart is assessed by palpation and direct visual inspection after sternotomy and pericardiotomy. The aortopulmonary window and superior and inferior vena cava are dissected. After the aortic stenosis is closed, a 1 L of HTK cardioplegia is delivered through the aortic cannula. The pulmonary cannula is left open to drain into the OCS reservoir. The coronary flow is maintained around 700-800 ml/min and the mean aortic pressure is controlled by manipulating the maintenance solution rate and aortic blood flow. Periodic arterial and venous blood gas is performed to define the trend in lactate levels and assess LV contractility. The heart is shifted to the OCS tray, a sterile covering is placed over it, and the lid of the OCS tray is sealed shut.
OCS systems are one of the most important safety components in modern vehicles. Sensor innovation is one of the key factors driving market growth. In addition, a growing demand for passive automotive safety technologies is expected to boost market growth in the coming years. The global ocs system market is segmented by component type, with sensors holding the largest share of the market due to their extensive usage in passive vehicle safety systems. Other segments include airbag control unit, seat belt tension sensor, and others. The market is categorized by geography, with North America and Europe expected to dominate the global market share in terms of revenue.